Acute Pain & Post-Operative
Post-operative pain remains a critical challenge in surgical recovery, impacting patient outcomes and satisfaction. Our Acute Pain research focuses on evaluating innovative therapies that improve pain control, reduce opioid reliance, and enhance recovery across diverse surgical populations.
Studies Conducted
Acute & post-surgical pain focus
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Trial Participants
Enrolled in acute pain studies
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Active Sites
Specialized research locations
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Overview
Leading Acute Pain Clinical Research
Our acute pain clinical research combines scientific expertise with operational excellence to support post-operative studies from early-phase trials through late-stage development.
We specialize in designing trials that assess rapid-onset analgesics, non-opioid alternatives, and multimodal pain management strategies. Our teams ensure precise data collection, patient safety, and efficient execution across all study phases.
Our sites support a wide range of surgical models, enabling reliable evaluation of pain intensity, duration, and treatment response in real-world clinical settings.
Conditions Covered
Acute Pain Conditions We Research
Our acute pain research sites support a broad spectrum of post-operative and procedure-related pain conditions.
Post-Surgical Pain
Orthopedic Surgery Pain
Abdominal Surgery Pain
Dental Pain
Soft Tissue Injury Pain
Neuropathic Post-Surgical Pain
Acute Musculoskeletal Pain
Trauma-Related Pain
Burn Injury Pain
Post-Cesarean Pain
Our Approach
Why Sponsors Choose CenExel for Acute Pain
Our acute pain expertise goes beyond patient enrollment — we deliver scientific insight, rapid execution, and reliable outcomes.
01
Rapid Study Start-Up
Our experienced teams enable fast site activation and efficient study execution for time-sensitive acute pain trials.
02
Diverse Surgical Models
We support multiple surgical indications, providing flexibility and robust patient recruitment.
03
Opioid-Sparing Focus
Expertise in evaluating non-opioid and multimodal pain management strategies.
04
High Enrollment Performance
Consistent delivery of strong enrollment through targeted recruitment strategies.
Phase Coverage
Supported Trial Phases
We support acute pain clinical trials across all phases — from first-in-human studies to Phase IV post-marketing research, ensuring high-quality execution and reliable outcomes.
Active across all phases
Phase I
Phase II
Phase III
Phase IV
Our early phase capabilities include pharmacodynamic biomarker strategies, first-in-human studies, and proof-of-concept trial design — guided by Chief Scientific Officer Dr. Larry Ereshefsky, an internationally recognized KOL in CNS research with over 30 years of early phase expertise.
Acute Pain Task Force
CenExel’s Acute Pain Task Force brings together experienced investigators, anesthesiologists, and pain specialists to support complex post-operative trials. These teams focus on optimizing study design, improving patient recruitment, and ensuring high-quality data across diverse surgical indications.
Active Sites
15 Sites
CenExel Gaithersburg
CenExel Garden Grove
CenExel Atlanta
CenExel Marlton
CenExel Hollywood
Related Therapeutic Areas
Also in Pain & Inflammation
Therapeutic Area
Behavioral Health
Mood disorders, anxiety, and co-occurring behavioral conditions.
Therapeutic Area
Psychiatry
Mental health conditions including depression, schizophrenia, and anxiety disorders.
Therapeutic Area
CNS
Central nervous system disorders supported by decades of clinical expertise.