Pain Management & Neurology
Chronic Pain
Chronic pain affects millions worldwide, significantly impacting quality of life and daily functioning. CenExel partners with sponsors to advance innovative therapies that address both the physical and neurological aspects of chronic pain—delivering hope to patients across diverse populations.



Studies Conducted
Trial Participants
Active Sites
Leading Chronic Pain Clinical Research
Chronic pain research requires specialized scientific knowledge and patient-centered execution. CenExel’s experienced teams integrate clinical expertise, advanced trial design, and operational excellence to ensure efficient study delivery.
Our research spans a wide range of chronic pain conditions, incorporating innovative endpoints, patient-reported outcomes, and biomarker strategies to improve trial success.
We support studies across diverse populations, including adult, geriatric, and underserved patient groups.
Chronic Pain Conditions We Research
Our chronic pain research sites support a broad spectrum of conditions, addressing both acute and long-term pain disorders.
Neuropathic Pain
Fibromyalgia
Chronic Lower Back Pain
Migraine & Chronic Headache
Osteoarthritis Pain
Rheumatoid Arthritis Pain
Cancer-Related Pain
Post-Surgical Pain
Complex Regional Pain Syndrome (CRPS)
Diabetic Neuropathy
Why Sponsors Choose CenExel for Chronic Pain
Our expertise extends beyond enrollment—we provide scientific insight, operational precision, and high-quality data for regulatory success.
01
Pain Assessment Expertise
Our teams utilize validated pain scales, digital endpoints, and patient-reported outcomes to ensure accurate and reliable data collection.
02
Advanced Trial Design
We support adaptive trial designs, biomarker integration, and innovative methodologies to improve efficiency and outcomes.
03
Diverse Patient Access
Access to diverse patient populations across multiple U.S. regions ensures representative and inclusive clinical trials.
04
Proven Enrollment Success
Our recruitment strategies consistently meet and exceed enrollment goals, even for complex chronic pain studies.
Supported Trial Phases
CenExel supports chronic pain trials across all phases—from early-stage first-in-human studies to large-scale Phase IV and post-marketing research.
Active across all phases
Phase I
Phase II
Phase III
Phase IV
Our early phase capabilities include pharmacodynamic biomarker strategies, first-in-human studies, and proof-of-concept trial design — guided by Chief Scientific Officer Dr. Larry Ereshefsky, an internationally recognized KOL in CNS research with over 30 years of early phase expertise.
Chronic Pain Task Force
CenExel supports a wide range of chronic pain indications, including neuropathic pain, musculoskeletal disorders, migraine, and rare pain conditions—across adult and geriatric populations.
Active Sites
15 Sites
Also in Pain & Neuroscience
Therapeutic Area
Neurology
Research in neurological disorders impacting pain perception and nerve function.
Therapeutic Area
Rheumatology
Studies focused on inflammatory and autoimmune conditions causing chronic pain.
Therapeutic Area
Behavioral Health
Addressing the psychological impact of chronic pain and related conditions.
